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Our Sacraments

At the Church of the Sacred Synthesis, we work with two primary sacraments, Psilomethoxin and 5-MeO-DMT, each offering unique and complementary effects on consciousness, emotional well-being, and nervous system regulation.

These substances are administered and received strictly within the spiritual framework of our Church. They are not medical treatments, prescriptions, or cures. While grounded in neurochemical science, their use is sacramental, and any exploration with these compounds should be done in consultation with your licensed medical or mental health providers.
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Sacraments

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Psilomethoxin

Psilomethoxin is a sacramental compound cultivated by introducing 5-MeO-DMT during the growth of psilocybin mushrooms. This process yields a synthesis of psilocin and 5-MeO-DMT, creating a gentle, non-visual serotonin-analog known for supporting emotional balance, clarity, parasympathetic activation, and neuroplasticity. It is available in capsule or powder form and commonly used for microdosing, daily ritual, or the 30-day protocol.
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Jaguar Light Wand

The Jaguar Light Wand is a handheld vapor device offering rapid-onset, adjustable low-dose 5-MeO-DMT for swift clarity, ego softening, connection and deep nervous-system relaxation.
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Unity Mist

Jaguar Unity Mist is a low-dose, easy-to-use 5-MeO-DMT nasal sacrament that offers a calm 60–90 minute journey into emotional softening, grounded presence, and deep inner clarity.
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Coyote Cacao – Lovers Edition

This blend combines organic ceremonial-grade Ecuadorian cacao with a gentle microdose of Psilomethoxin to create a daily ritual that supports mental clarity, clean energy, and heart-centered presence. Each order includes six handcrafted hearts, and every individual heart holds approximately twenty grams of cacao with natural neuromodulators and antioxidants, along with 150 mg of Psilomethoxin.
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The Sacred Bundle

A curated constellation of our most beloved sacraments – crafted to guide you into deep coherence, emotional liberation, and transformational clarity.
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Sacrament

Psilomethoxin
5-MeO-DMT

Primary Receptor Sites

Primarily 5-HT1A , some 5-HT2A
Primarily 5-HT1A, some 5-HT2A

Form

Capsules or powder
Jaguar Light Wand / Unity Mist

Core Effects

Emotional insight, grounded presence, heart-opening
Ego dissolution, nonduality, timeless stillness

Psilomethoxin:
A Bridge Between Worlds

What is Psilomethoxin?

Psilomethoxin is a novel compound formed through a sacramental alchemical process in which 5-MeO-DMT is introduced during the cultivation of psilocybin-containing mushrooms. The result is a mushroom that expresses:
  • Psilocin – the active ingredient in psilocybin mushrooms
  • 5-MeO-DMT – a powerful compound found in toads and plants
  • Psilomethoxin – an emergent compound from their synthesis

How it Works in the Brain:

  • Psilocin primarily activates the 5-HT2A receptors, associated with perception, emotion, and ego.
  • 5-MeO-DMT, present in trace amounts, engages the 5-HT1A receptors, which modulate calm, presence, and introspection.
  • Psilomethoxin is believed to engage both pathways, producing a blend of embodied insight and serenity.

Reported Effects:

  • Less visual than typical psilocybin journeys
  • Smooth onset and gentle return
  • Emotional clarity and heart-centered awareness
  • Grounded perception with spiritual undertones
  • Often described as “meditative mushrooms” or a “peaceful 5-MeO journey”

Used Within the Church To Support:

  • Integration of life transitions
  • Heart-mind alignment
  • Conscious evolution with intention and presence

5-MeO-DMT:
The Light of Nonduality

What is 5-MeO-DMT?

5-MeO-DMT is a naturally occurring compound found in the Sonoran Desert Toad (Incilius alvarius) and certain plants. It is also produced endogenously in the human body. Known for its intensity and fast onset, 5-MeO-DMT is sometimes called “The God Molecule” for its ability to dissolve ego structures and open consciousness to nondual awareness.

Church Administration Formats:

  • Jaguar Light Wand: a microdose, handheld vapor device for a rapid onset, incrementally increased dosing experience
  • Jaguar Unity Mist: a microdose nasal spray format intended for gentler, elongated experience

Neuroscientific Profile:

  • Primarily activates 5-HT1A receptors, associated with calm, surrender, and ego dissolution
  • Secondary interaction with 5-HT2A receptors, allowing some perceptual shifts
  • Known to disrupt the brain’s Default Mode Network (DMN), which governs self-referencing and mental loops

Reported Effects:

  • A sense of becoming light, energy, or pure awareness
  • Deep nervous system reset
  • Timeless stillness and profound inner silence
  • At high dose, full ego dissolution and merging with “the void”

Used Within the Church To Support:

  • Spiritual surrender
  • Nervous system re-regulation
  • Direct communion with non-ordinary states of consciousness

Disclaimer

These sacraments are offered as part of our religious and spiritual practice under the protections afforded to sincere religious use.
This is not medical advice. These substances are not intended to diagnose, treat, or cure any condition, nor are they a substitute for professional healthcare. Please consult with your licensed medical provider before making decisions about your mental, emotional, or physical health.
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Final Note

Within the Church of the Sacred Synthesis, we view these sacraments as tools for intentional inner exploration—not quick fixes. They can open access to deeper awareness, but only you can choose how to respond to what is revealed.

If you feel called to walk this path with humility, curiosity, and responsibility, you are welcome here, and if you need support please reach out!

Our Sacraments

Members Only

Jaguar Unity Mist – User Guide (PDF)

A guide to using Unity Mist safely, featuring guidelines, dosing instructions, safety precautions, and integration tips to enhance your journey of transformation.
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Jaguar Light Wand – User Guide (PDF)

A beautifully designed PDF guide for Jaguar Light Wand users, covering safe usage, dosing, preparation, and post journey integration. Created to help you get the most from your experience with clarity and intention.
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Members Only

The Sacred Bundle

A curated constellation of our most beloved sacraments – crafted to guide you into deep coherence, emotional liberation, and transformational clarity.
Shop Now

Members Only

Coyote Cacao – Lovers Edition

This blend combines organic ceremonial-grade Ecuadorian cacao with a gentle microdose of Psilomethoxin to create a daily ritual that supports mental clarity, clean energy, and heart-centered presence. Each order includes six handcrafted hearts, and every individual heart holds approximately twenty grams of cacao with natural neuromodulators and antioxidants, along with 150 mg of Psilomethoxin.
Shop Now
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